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Anticonvulsants Sinemet (Generic)

Sinemet (Generic)
What should I know about Sinemet

Sinemet (Carbidopa/levodopa), likewise called levocarb and also co-careldopa, is the combination of both medications carbidopa as well as levodopa. This mix drug is utilized to cure signs of Parkinson's condition or Parkinson-like symptoms (such as shakiness, tightness, difficulty moving). Parkinson's condition is thought to be triggered by also little of a normally occurring compound (dopamine) in the mind. Levodopa adjustments right into dopamine in the brain, helping to control movement. Carbidopa avoids the break down of levodopa in the bloodstream so extra levodopa could go into the brain. Carbidopa can additionally minimize a few of levodopa's negative effects such as queasiness as well as vomiting. If you already take levodopa, you need to stop taking it a minimum of 12 hours prior to you begin taking Sinemet. Sinemet could be taken with or with no a meal. You should take your dosages at regular periods to keep a consistent amount of the drug in your body at all times. Get your prescription re-filled prior to you lack medicine completely.Do not crush, chew, break, or open up a Sinemet capsule. Swallow it entire. You could discover that your sweat, pee, or saliva shows up dark in color, including red, brownish, or black. This is not a dangerous adverse effects, but it might cause staining of your garments or bed sheets. Ask for urgent medical assistance if you have any one of these signs of an allergic response: hives; trouble breathing; swelling of your lips, face, tongue, or throat. Tell your medical professional without delay if you experience any one of these severe negative effects: troubled muscle movements in your eyes, tongue, jaw, or neck; worsening of shakes.

Sinemet Purchase

Acquiring Sinemet at our website is very easy as well as painless. But at the same time you ought to take your therapy very carefully. Even if you think that info discussed above suffices to start taking this medication for healing, you need to consult your doctor initially.

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Generic Sinemet is used to treat Parkinson symptoms such as muscle stiffness, tremors, spasms, and poor muscle control. This medication is also used to treat Parkinson symptoms caused by carbon monoxide poisoning or manganese intoxication.

The active ingredient in Generic Sinemet, Levodopa is converted to dopamine via the action of a naturally occurring enzyme called DOPA decarboxylase. This occurs both in the peripheral circulation and in the central nervous system after levodopa has crossed the blood brain barrier. Activation of central dopamine receptors improves the symptoms of Parkinson's disease.

How to take

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Generic Sinemet can be taken with or without food. Take your doses at regular intervals to keep a steady amount of the drug in your body at all times.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

The regular tablet can be broken or crushed if needed to make it easier to swallow.

To take the orally disintegrating tablet:

  • Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
  • Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.
  • Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves.

Side effects

You may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • restless muscle movements in your eyes, tongue, jaw, or neck;
  • worsening of tremors (uncontrolled shaking);
  • high fever, stiff muscles, sweating, fast or uneven heartbeats, rapid breathing, feeling like you might pass out;
  • seizure (convulsions);
  • painful or difficult urination;
  • severe nausea, vomiting, or diarrhea;
  • uneven heart rate or fluttering in your chest;
  • confusion, hallucinations, anxiety, agitation, depressed mood, thoughts of suicide or hurting yourself;
  • chest pain or heavy feeling, pain spreading to the arm or shoulder.

Less serious side effects may include:

  • mild nausea, dry mouth, loss of appetite, heartburn, diarrhea, constipation;
  • headache, dizziness, drowsiness, blurred vision;
  • sneezing, stuffy nose, cough, or other cold symptoms;
  • sleep problems (insomnia), strange dreams;
  • muscle pain, numbness or tingly feeling; or
  • skin rash or itching.

This is not a complete list of side effects and others may occur.


Do not take Generic Sinemet if:

  • you have an allergy to Generic Sinemet
  • you have any unusual skin lumps or moles which have not been examined by your doctor,
  • or if you have ever had skin cancer or melanoma
  • you have a type of glaucoma called narrow-angle glaucoma

Avoid taking iron supplements or eating a diet that is high in protein (protein sources include meat, eggs, and cheese). These things can make it harder for your body to digest and absorb carbidopa and levodopa. Talk with your doctor or nutrition counselor about the best foods to eat while you are taking this medication.

If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.

Drug interactions

Tell your doctor about all other medicines you use, especially:

  • other Parkinson's medications;
  • Generic Maxolon (Reglan);
  • isoniazid (Nydrazid);
  • phenytoin (Dilantin);
  • papaverine (Pavabid, Papacon, Pavagen, Pavacot);
  • blood pressure medication;
  • an antidepressant such as amitriptyline (Elavil, Vanatrip), doxepin (Sinequan), Generic Nortriptyline (Pamelor), and others; or
  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), prochlorperazine (Compazine), risperidone (Risperdal), and others;

This list is not complete and other drugs may interact with Generic Sinemet.

Missed dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


Store at room temperature away from moisture, heat, and light.


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